Reference memory effects of distributed practice on radial maze learning by rats

Differential effects of scopolamine on working and reference memory of rats in the radial maze.

Anticholinergics have often been found to impair choice accuracy in the radial maze. Some researchers have suggested that this indicates involvement of cholinergically innervated structures in cognitive mapping while others argue that these structures mediate working memory. However, most results are open to either interpretation since the baiting method did not allow a distinction between refe...

Effect of Ovariectomy on Reference Memory Version of Morris Water Maze in Young Adult Rats

Background: The effect of ovariectomy and accompanying sudden loss of circulating gonad hormones on spatial learning performance in the young adult rats was examined. We hypothesized that spatial learning and memory in a considerable number of women who undergo a surgical menopause and estrogen deprivation before their natural menopause be impaired. Methods: In this study, we used 26 Wistar ra...

The Interaction Between Spatial Working and Reference Memory in Rats on a Radial Maze

Chlordiazepoxide specifically impairs nonspatial reference memory in the cued radial arm maze in rats.

Anxiolytic benzodiazepines, at low doses, reportedly impair the radial arm maze with nonspatial visual/tactile but not spatial cues. We replicated the former result controlling for changes in drug state and cue effectiveness. Rats learned an eight-arm radial maze with reward in only four arms. The reward varied in spatial position from trial to trial but was always cued by a piece of sandpaper ...

evaluation of systemic effects of ginger fractions on salivation in rats

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